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Comment
. 2015 Sep 15;43(3):414-5.
doi: 10.1016/j.immuni.2015.08.025.

IL-17A Has Some Nerve!

James A Sanford  1 , Richard L Gallo  2
Affiliations
Comment

IL-17A Has Some Nerve!

James A Sanford et al. Immunity. .

Abstract

Sensory neurons are important in controlling cutaneous inflammation, but the role of neurons in host antimicrobial defense was relatively unknown. Kaplan and colleagues now demonstrate that nociceptive fibers within the dermis play a crucial role in antifungal defenses through their influence on dermal dendritic cells and induction of IL-17A.

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