Close Encounters of the Tertiary Kind
- PMID: 26377895
- DOI: 10.1016/j.immuni.2015.08.022
Close Encounters of the Tertiary Kind
Abstract
Elucidating the function of tumor-infiltrating regulatory T (Treg) cells has been difficult. In this issue of Immunity, Joshi et al. (2015) demonstrate that Treg cells associated with murine lung cancers are found within tertiary lymphoid structures and actively restrain effector T cells at the tumor site.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses.Immunity. 2015 Sep 15;43(3):579-90. doi: 10.1016/j.immuni.2015.08.006. Epub 2015 Sep 1. Immunity. 2015. PMID: 26341400 Free PMC article.