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Review
. 2015 Nov;17(11):87.
doi: 10.1007/s11920-015-0628-3.

Premenstrual Dysphoric Disorder: Epidemiology and Treatment

Liisa Hantsoo  1 , C Neill Epperson  2
Affiliations
Review

Premenstrual Dysphoric Disorder: Epidemiology and Treatment

Liisa Hantsoo et al. Curr Psychiatry Rep. 2015 Nov.

Abstract

Recently designated as a disorder in the DSM-5, premenstrual dysphoric disorder (PMDD) presents an array of avenues for further research. PMDD's profile, characterized by cognitive-affective symptoms during the premenstruum, is unique from that of other affective disorders in its symptoms and cyclicity. Neurosteroids may be a key contributor to PMDD's clinical presentation and etiology, and represent a potential avenue for drug development. This review will present recent literature on potential contributors to PMDD's pathophysiology, including neurosteroids and stress, and explore potential treatment targets.

Keywords: GABA; Menstrual cycle; PMDD; PMS; Premenstrual.

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References

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