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Randomized Controlled Trial
. 2015;11(12):2883-94.
doi: 10.1080/21645515.2015.1070996. Epub 2015 Sep 17.

Overcoming barriers to HPV vaccination: A randomized clinical trial of a culturally-tailored, media intervention among African American girls

Ralph J DiClemente  1   2 , Colleen Crittenden Murray  3 , Tracie Graham  4 , Julia Still  5
Affiliations
Randomized Controlled Trial

Overcoming barriers to HPV vaccination: A randomized clinical trial of a culturally-tailored, media intervention among African American girls

Ralph J DiClemente et al. Hum Vaccin Immunother. 2015.

Abstract

Although genital HPV is the most prevalent STI in the US, rates of vaccination uptake among high-risk subgroups remain low. Investigations of vaccine compliance have mainly targeted mother-daughter dyads, which in some settings may prove difficult. This study examines an innovative culturally tailored, computer-delivered media-based strategy to promote HPV vaccine uptake. Data, inclusive of sociodemographics, sexual behaviors, knowledge, attitudes, and beliefs about HPV and vaccination were collected via ACASI from 216 African American adolescent females (ages 14-18 years) seeking services in family planning and STI public health clinics in metropolitan Atlanta. Data were obtained prior to randomization and participation in an interactive media-based intervention designed to increase HPV vaccination uptake. Medical record abstraction was conducted 7 month post-randomization to assess initial vaccine uptake and compliance. Participants in the intervention were more compliant to vaccination relative to a placebo comparison condition (26 doses vs. Seventeen doses; p=0.12). However, vaccination series initiation and completion were lower than the national average. Thorough evaluation is needed to better understand factors facilitating HPV vaccine uptake and compliance, particularly perceived susceptibility and the influence of the patient-provider encounter in a clinical setting.

Keywords: HPV; adolescent; media intervention; vaccination uptake.

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Figures

Figure 1.
Figure 1.
Application of IMB model constructs to guide development of the Girls OnGuard intervention.
Figure 2.
Figure 2.
Consort diagram of Girls OnGuard study allocation.
See this image and copyright information in PMC

References

    1. Centers for Disease Control and Prevention Fact sheet—Incidence, prevalence, and cost of sexually transmitted infections in the United States. Available online: http://www.cdc.gov/std/stats/sti-estimates-fact-sheet-feb-2013.pdf [accessed 03.October.13]
    1. Moscicki AB. HPV infections in adolescents. Dis Markers 2007; 23(4): 229-234; PMID:17627058; http://dx.doi.org/10.1155/2007/136906 - DOI - PMC - PubMed
    1. Dunne EF, Unger ER, Sternberg M, et al.. Prevalence of HPV infection among females in the United States. JAMA 2007; 297: 813-819; PMID:17327523; http://dx.doi.org/10.1001/jama.297.8.813 - DOI - PubMed
    1. Kahn JA, Lan D, Kahn RS. Sociodemographic factors associated with high risk human papillomavirus infection. Obstet Gynecol 2007; 110(1): 87-95; PMID:17601901; http://dx.doi.org/10.1097/01.AOG.0000266984.23445.9c - DOI - PubMed
    1. Moscicki AB. Impact of HPV infection in adolescent populations. J Adolesc Health 2005; 37(6): S3-S9; PMID:16310138; http://dx.doi.org/10.1016/j.jadohealth.2005.09.011 - DOI - PubMed

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