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. 2015 Jul-Aug;20(4):290-8.
doi: 10.5863/1551-6776-20.4.290.

Impact of Clinical Pharmacist on the Pediatric Intensive Care Practice: An 11-Year Tertiary Center Experience

Sandeep Tripathi  1 , Heidi M Crabtree  2 , Karen R Fryer  1 , Kevin K Graner  2 , Grace M Arteaga  1
Affiliations

Impact of Clinical Pharmacist on the Pediatric Intensive Care Practice: An 11-Year Tertiary Center Experience

Sandeep Tripathi et al. J Pediatr Pharmacol Ther. 2015 Jul-Aug.

Abstract

Objectives: With increasing complexity of critical care medicine comes an increasing need for multidisciplinary involvement in care. In many institutions, pharmacists are an integral part of this team, but long-term data on the interventions performed by pharmacists and their effects on patient care and outcomes are limited. We aimed to describe the role of pediatric clinical pharmacists in pediatric intensive care unit (PICU) practice.

Methods: We retrospectively reviewed the records of pharmacy interventions in the PICU at the Mayo Clinic in Rochester, Minnesota, from 2003-2013, with a distinct period of increased pharmacist presence in the PICU from 2008 onward. We compared demographic and outcome data on patients who did and who did not have pharmacy interventions during 2 periods (2003-2007 and 2008-2013).

Results: We identified 27,773 total interventions by pharmacists during the 11-year period, of which 79.8% were accepted by the clinical team. These interventions were made on 10,963 unique PICU admissions and prevented 5867 order entry errors. Pharmacists' interventions increased year over year, including a significant change in 2008. Patients who required pharmacy involvement were younger, sicker, and had longer intensive care unit, hospital, and ventilator duration. Average central line infections and central line entry rates decreased significantly over the study period.

Conclusions: Increased pharmacist presence in the PICU is associated with increased interventions and prevention of adverse drug events. Pharmacist participation during rounds and order entry substantially improved the care of critically sick children and should be encouraged.

Keywords: adverse drug reaction; catheter-related infections; medication errors; pediatric intensive care units; pharmacists.

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References

    1. Kim MM, Barnato AE, Angus DC et al. The effect of multidisciplinary care teams on intensive care unit mortality [erratum in: Arch Intern Med. 2010;170(10):867] Arch Intern Med. 2010;170(4):369–376. - PMC - PubMed
    1. Brilli RJ, Spevetz A, Branson RD. The American College of Critical Care Medicine Guidelines for the Definition of an Intensivist and the Practice of Critical Care Medicine: critical care delivery in the intensive care unit: defining clinical roles and the best practice model. Crit Care Med. 2001;29(10):2007–2019. et al; American College of Critical Care Medicine Task Force on Models of Critical Care Delivery. - PubMed
    1. Sanghera N, Chan PY, Khaki ZF et al. Interventions of hospital pharmacists in improving drug therapy in children: a systematic literature review. Drug Saf. 2006;29(11):1031–1047. - PubMed
    1. Kucukarslan SN, Peters M, Mlynarek M, Nafziger DA. Pharmacists on rounding teams reduce preventable adverse drug events in hospital general medicine units. Arch Intern Med. 2003;163(17):2014–2018. - PubMed
    1. Bond CA, Raehl CL, Franke T. Clinical pharmacy services and hospital mortality rates. Pharmacotherapy. 1999;19(5):556–564. - PubMed

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