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Comment
. 2015 Sep 18;349(6254):1282-3.
doi: 10.1126/science.aad0584.

GENETICS. Strength in small numbers

Sarah Tishkoff  1
Affiliations
Comment

GENETICS. Strength in small numbers

Sarah Tishkoff. Science. .
No abstract available

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Figures

None
Global distribution of locally adaptive traits
Adaptation to diverse environments during human evolution has resulted in phenotypes that are at the extremes of the global distribution. Fumagalli et al. have integrated scans of natural selection and GWAS to identify genetic loci associated with adaptation to an Arctic environment.
See this image and copyright information in PMC

Comment on

  • Greenlandic Inuit show genetic signatures of diet and climate adaptation.
    Fumagalli M, Moltke I, Grarup N, Racimo F, Bjerregaard P, Jørgensen ME, Korneliussen TS, Gerbault P, Skotte L, Linneberg A, Christensen C, Brandslund I, Jørgensen T, Huerta-Sánchez E, Schmidt EB, Pedersen O, Hansen T, Albrechtsen A, Nielsen R. Fumagalli M, et al. Science. 2015 Sep 18;349(6254):1343-7. doi: 10.1126/science.aab2319. Science. 2015. PMID: 26383953

References

    1. Wood AR, et al. Nat Genet. 2014;46:1173. - PMC - PubMed
    1. Locke AE, et al. Nature. 2015;518:197. - PMC - PubMed
    1. Fumagalli M, et al. Science. 2015;349:1343. - PubMed
    1. Voight BF, et al. PLOS Genet. 2012;8:e1002793. - PMC - PubMed
    1. Cohen JC, Hobbs HH. Science. 2013;340:689. - PMC - PubMed

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