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. 2016 Mar;20(3):679-86.
doi: 10.1007/s10461-015-1197-5.

Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV

William C Becker  1   2 , Kirsha Gordon  3 , E Jennifer Edelman  4 , Robert D Kerns  5   6 , Stephen Crystal  7 , James D Dziura  4 , Lynn E Fiellin  4 , Adam J Gordon  8 , Joseph L Goulet  5   6 , Amy C Justice  3   4 , David A Fiellin  4
Affiliations

Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV

William C Becker et al. AIDS Behav. 2016 Mar.

Erratum in

Abstract

Harms of opioid analgesics, especially high-dose therapy among individuals with comorbidities and older age, are increasingly recognized. However, trends in opioid receipt among HIV-infected patients are not well characterized. We examined trends, from 1999 to 2010, in any and high-dose (≥120 mg/day) opioid receipt among patients with and without HIV, by age strata, controlling for demographic and clinical correlates. Of 127,216 patients, 64 % received at least one opioid prescription. Opioid receipt increased substantially among HIV-infected and uninfected patients over the study; high-dose therapy was more prevalent among HIV-infected patients. Trends in high-dose receipt stratified by three age groups revealed an increasing trend in each age strata, higher among HIV-infected patients. Correlates of any opioid receipt included HIV, PTSD and major depression. Correlates of high-dose receipt included HIV, PTSD, major depression and drug use disorders. These findings suggest a need for appropriate balance of risks and benefits, especially as these populations age.

Keywords: Aging; Analgesics; Chronic; Human immunodeficiency virus; Opioids; Pain.

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Figures

Fig. 1
Fig. 1
Trends in any opioid receipt, overall and by HIV status
Fig. 2
Fig. 2
Trends in high-dose opioid receipt, overall and by HIV status (asterisk)
Fig. 3
Fig. 3
a High-dose opioid receipt by HIV status, age <45. b High-dose opioid receipt by HIV status, age 45–64. c High-dose opioid receipt by HIV status, age ≥ 65
See this image and copyright information in PMC

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