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Comment
. 2015 Nov;5(11):1117.
doi: 10.1158/2159-8290.CD-NB2015-131. Epub 2015 Sep 18.

Melanoma Drug Works in Other Tumors

No authors listed
Comment

Melanoma Drug Works in Other Tumors

No authors listed. Cancer Discov. 2015 Nov.

Abstract

In a phase II basket trial, vemurafenib, an enzyme inhibitor prescribed for certain BRAF V600-mutant melanomas, proved effective in some nonmelanoma cancers that also carried a BRAF V600 mutation.

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  • Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations.
    Hyman DM, Puzanov I, Subbiah V, Faris JE, Chau I, Blay JY, Wolf J, Raje NS, Diamond EL, Hollebecque A, Gervais R, Elez-Fernandez ME, Italiano A, Hofheinz RD, Hidalgo M, Chan E, Schuler M, Lasserre SF, Makrutzki M, Sirzen F, Veronese ML, Tabernero J, Baselga J. Hyman DM, et al. N Engl J Med. 2015 Aug 20;373(8):726-36. doi: 10.1056/NEJMoa1502309. N Engl J Med. 2015. PMID: 26287849 Free PMC article. Clinical Trial.

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