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Editorial
. 2015 Oct 13;6(31):30445-6.
doi: 10.18632/oncotarget.5720.

Disconnect between EMT and metastasis in pancreas cancer

Martin C Whittle  1 , Sunil R Hingorani  1   2   3
Affiliations
Editorial

Disconnect between EMT and metastasis in pancreas cancer

Martin C Whittle et al. Oncotarget. .
No abstract available

Keywords: Chromosome Section; RUNX3; SMAD4.

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Figures

Figure 1
Figure 1. EMT-competent and incompetent mechanisms of metastasis
Invasion and intravasation of pancreas cancer cells can occur by EMT-dependent or EMT-independent mechanisms. EMT-competent cells likely disseminate as individual migrating cells, whereas EMT-incompetent cells may favor clustered migration. Individual circulating tumor cells (CTC) are more abundant and exhibit increased motility compared to CTC clusters, however clustered CTC are more likely to survive in the bloodstream and colonize distant sites.
See this image and copyright information in PMC

References

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