Genetics of Breast and Gynecologic Cancers (PDQ®): Health Professional Version
- PMID: 26389210
- Bookshelf ID: NBK65767
Genetics of Breast and Gynecologic Cancers (PDQ®): Health Professional Version
Excerpt
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the genetics of breast and gynecologic cancers. It is intended as a resource to inform and assist clinicians in the care of their patients. It does not provide formal guidelines or recommendations for making health care decisions.
This summary is reviewed regularly and updated as necessary by the PDQ Cancer Genetics Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH).
Keywords: breast cancer; cancer genetics; endometrial cancer; ovarian epithelial cancer.
Sections
- Executive Summary
- Introduction
- Penetrance of Inherited Susceptibility to Hereditary Breast and/or Gynecologic Cancers
- Genes Associated With Breast and/or Gynecologic Cancer Susceptibility
- High-Penetrance Breast and/or Gynecologic Cancer Susceptibility Genes
- Moderate-Penetrance Genes Associated With Breast and/or Gynecologic Cancers
- Single Nucleotide Variant–Associated Cancer Risks
- Psychosocial Issues in Hereditary Breast and Gynecologic Cancers
- Latest Updates to This Summary (03/06/2025)
- About This PDQ Summary
References
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- American Cancer Society: Cancer Facts and Figures 2025. American Cancer Society, 2025. Available online. Last accessed January 16, 2025.
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- Ravdin PM, Cronin KA, Howlader N, et al.: The decrease in breast-cancer incidence in 2003 in the United States. N Engl J Med 356 (16): 1670-4, 2007. - PubMed
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- Feuer EJ, Wun LM, Boring CC, et al.: The lifetime risk of developing breast cancer. J Natl Cancer Inst 85 (11): 892-7, 1993. - PubMed
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- Yang Q, Khoury MJ, Rodriguez C, et al.: Family history score as a predictor of breast cancer mortality: prospective data from the Cancer Prevention Study II, United States, 1982-1991. Am J Epidemiol 147 (7): 652-9, 1998. - PubMed
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