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Review
. 2015 Sep 16;13(9):5920-46.
doi: 10.3390/md13095920.

Therapies from Fucoidan: An Update

Janet Helen Fitton  1 , Damien N Stringer  2 , Samuel S Karpiniec  3
Affiliations
Review

Therapies from Fucoidan: An Update

Janet Helen Fitton et al. Mar Drugs. .

Abstract

Fucoidans are a class of sulfated fucose-rich polysaccharides found in brown marine algae and echinoderms. Fucoidans have an attractive array of bioactivities and potential applications including immune modulation, cancer inhibition, and pathogen inhibition. Research into fucoidan has continued to gain pace over the last few years and point towards potential therapeutic or adjunct roles. The source, extraction, characterization and detection of fucoidan is discussed.

Keywords: anti-bacterial; anti-cancer; anti-inflammatory; anti-viral; immune modulation; sulfated carbohydrate.

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References

    1. Berteau O., Mulloy B. Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide. Glycobiology. 2003;13:29–40. doi: 10.1093/glycob/cwg058. - DOI - PubMed
    1. Kannan R.R., Arumugam R., Anantharaman P. Pharmaceutical potential of a fucoidan-like sulphated polysaccharide isolated from Halodule pinifolia. Int. J. Biol. Macromol. 2013;62:30–34. doi: 10.1016/j.ijbiomac.2013.08.005. - DOI - PubMed
    1. Fitton J. Therapies from fucoidan; multifunctional marine polymers. Mar. Drugs. 2011;9:1731–1760. doi: 10.3390/md9101731. - DOI - PMC - PubMed
    1. Kwak J.Y. Fucoidan as a marine anticancer agent in preclinical development. Mar. Drugs. 2014;12:851–870. doi: 10.3390/md12020851. - DOI - PMC - PubMed
    1. Pomin V.H. Fucanomics and galactanomics: Current status in drug discovery, mechanisms of action and role of the well-defined structures. Biochim. Biophys. Acta. 2012;1820:1971–1979. doi: 10.1016/j.bbagen.2012.08.022. - DOI - PubMed

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