Is the MC1R variant p.R160W associated with Parkinson's?
- PMID: 26389967
- PMCID: PMC4738170
- DOI: 10.1002/ana.24527
Is the MC1R variant p.R160W associated with Parkinson's?
Conflict of interest statement
POTENTIAL CONFLICTS OF INTEREST:
Dr. Morris reports grants from Medical Research Council UK, grants from Wellcome Trust, grants from Parkinson’s UK, grants from Ipsen Fund, during the conduct of the study; grants from Motor Neuron Disease Association, grants from Welsh Assembly Government, personal fees from Teva, personal fees from Abbvie, personal fees from Teva, personal fees from UCB, personal fees from Boerhinger-Ingelheim, personal fees from GSK, outside the submitted work.
Comment in
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Reply.Ann Neurol. 2016 Jan;79(1):161-3. doi: 10.1002/ana.24526. Epub 2015 Dec 12. Ann Neurol. 2016. PMID: 26389780 No abstract available.
Comment on
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The MC1R melanoma risk variant p.R160W is associated with Parkinson disease.Ann Neurol. 2015 May;77(5):889-94. doi: 10.1002/ana.24373. Epub 2015 Mar 13. Ann Neurol. 2015. PMID: 25631192
References
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- Raimondi S, Sera F, Gandini S, et al. MC1R variants, melanoma and red hair color phenotype: a meta-analysis. [Internet] Int J Cancer. 2008;122(12):2753–60. [cited 2015 Mar 18 ] Available from: http://www.ncbi.nlm.nih.gov/pubmed/18366057. - PubMed
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- Tell-Marti G, Puig-Butille JA, Potrony M, et al. The MC1R melanoma risk variant p.R160W is associated with Parkinson disease. [Internet] Ann Neurol. 2015;77(5):889–94. [cited 2015 Apr 24 ] Available from: http://www.ncbi.nlm.nih.gov/pubmed/25631192. - PubMed
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- Dong J, Gao J, Nalls M, et al. Susceptibility loci for pigmentation and melanoma in relation to Parkinson’s disease. [Internet] Neurobiol Aging. 2014;35(6):1512e5–10. [cited 2014 Sep 26 ] Available from: http://www.ncbi.nlm.nih.gov/pubmed/24439955. - PMC - PubMed
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- Gerstenblith MR, Goldstein AM, Fargnoli MC, et al. Comprehensive evaluation of allele frequency differences of MC1R variants across populations. [Internet] Hum Mutat. 2007;28(5):495–505. [cited 2015 Apr 27] Available from: http://www.ncbi.nlm.nih.gov/pubmed/17279550. - PubMed
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- G1100643/MRC_/Medical Research Council/United Kingdom
- Z01 AG000957/ImNIH/Intramural NIH HHS/United States
- Z01 AG000949/ImNIH/Intramural NIH HHS/United States
- R01 CA141668/CA/NCI NIH HHS/United States
- WT089698/WT_/Wellcome Trust/United Kingdom
- 076113/WT_/Wellcome Trust/United Kingdom
- K-1501/PUK_/Parkinson's UK/United Kingdom
- R01NS037167/NS/NINDS NIH HHS/United States
- Z01-AG000949-02/AG/NIA NIH HHS/United States
- R01 NS037167/NS/NINDS NIH HHS/United States
- R01CA141668/CA/NCI NIH HHS/United States
- G-1107/PUK_/Parkinson's UK/United Kingdom
- P50 NS071674/NS/NINDS NIH HHS/United States
- P50NS071674/NS/NINDS NIH HHS/United States
- Z01 ES101986/ImNIH/Intramural NIH HHS/United States
- G0700943/MRC_/Medical Research Council/United Kingdom
- MR/L501554/1/MRC_/Medical Research Council/United Kingdom
- WT089698 /Z/09/Z/WT_/Wellcome Trust/United Kingdom
- 083948/Z/07/z/WT_/Wellcome Trust/United Kingdom
- 085475/WT_/Wellcome Trust/United Kingdom
- WT_/Wellcome Trust/United Kingdom
- 090355/WT_/Wellcome Trust/United Kingdom
- MR/L023784/2/MRC_/Medical Research Council/United Kingdom
- MR/L010305/1/MRC_/Medical Research Council/United Kingdom
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