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Comment
. 2016 Mar;26(3):816-7.
doi: 10.1007/s00330-015-4019-2. Epub 2015 Sep 21.

What Evidence Is There That Gadobutrol Causes Increasing Signal Intensity within the Dentate Nucleus and Globus Pallidus on Unenhanced T1W MRI in Patients with RRMS?

Jacob Agris  1 , Hubertus Pietsch  2 , Thomas Balzer  3
Affiliations
Comment

What Evidence Is There That Gadobutrol Causes Increasing Signal Intensity within the Dentate Nucleus and Globus Pallidus on Unenhanced T1W MRI in Patients with RRMS?

Jacob Agris et al. Eur Radiol. 2016 Mar.

Abstract

KEY POINTS : The study by Stojanov et al does not convincingly support the conclusion that gadobutrol causes higher T1 enhancement in brain on unenhanced MRI. The study by Stojanov et al does not rule out confounding factors . The study by Stojanov et al has limitations in study design.

Keywords: Dentate nucleus; Gadobutrol; Globus pallidus; Signal intensity on unenhanced MRI.

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References

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