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Multicenter Study
. 2015 Nov;117(2):213-6.
doi: 10.1016/j.radonc.2015.09.016. Epub 2015 Sep 18.

Breast cancer following spinal irradiation for a childhood cancer: A report from the Childhood Cancer Survivor Study

Chaya S Moskowitz  1 , Jyoti Malhotra  2 , Joanne F Chou  3 , Suzanne L Wolden  3 , Rita E Weathers  4 , Marilyn Stovall  4 , Gregory T Armstrong  5 , Wendy M Leisenring  6 , Joseph P Neglia  7 , Leslie L Robison  5 , Kevin C Oeffinger  3
Affiliations
Multicenter Study

Breast cancer following spinal irradiation for a childhood cancer: A report from the Childhood Cancer Survivor Study

Chaya S Moskowitz et al. Radiother Oncol. 2015 Nov.

Abstract

It has been suggested that pediatric patients treated with spinal irradiation may have an elevated risk of breast cancer. Among a cohort of 363 long-term survivors of a pediatric central nervous system tumor or leukemia treated with spinal irradiation, there was little evidence of an increased breast cancer risk.

Keywords: Craniospinal irradiation; Late effects; Secondary breast cancer.

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Figures

Figure 1
Figure 1
Distribution of doses of spinal irradiation. The delivered doses of spinal irradiation are shown separately by childhood cancer diagnosis. The delivered doses for the three women diagnosed with breast cancer are denoted with an X.
See this image and copyright information in PMC

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