Neurodegeneration: The Size Takes It All
- PMID: 26394101
- DOI: 10.1016/j.cub.2015.07.062
Neurodegeneration: The Size Takes It All
Abstract
There is increasing computational evidence that the exceptionally high vulnerability of dopaminergic neurons in Parkinson's disease may be due to their unique axonal architecture and resulting metabolic needs. A new experimental study has actually demonstrated this.
Copyright © 2015 Elsevier Ltd. All rights reserved.
Comment on
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Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons.Curr Biol. 2015 Sep 21;25(18):2349-60. doi: 10.1016/j.cub.2015.07.050. Epub 2015 Aug 27. Curr Biol. 2015. PMID: 26320949
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