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. 2015 Sep 22:21:2845-50.
doi: 10.12659/MSM.894115.

Clinical Value of Contrast-Enhanced Ultrasound in Diagnosis of Hyperechoic Liver Lesions

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Clinical Value of Contrast-Enhanced Ultrasound in Diagnosis of Hyperechoic Liver Lesions

Junjie Liu et al. Med Sci Monit. .

Abstract

Background: The purpose of this study was to investigate the values of contrast-enhanced ultrasound (CEUS) in the diagnosis and differential diagnosis of hyperechoic liver lesions.

Material and methods: The CEUS findings of 102 patients with hyperechoic liver lesions identified by 2-dimensional ultrasound in the Affiliated Tumor Hospital of Guangxi Medical University were reviewed and analyzed.

Results: A total of 135 lesions were analyzed, of which malignant lesions were found in 72 patients and benign lesions in 63, with a CEUS accuracy rate of 91.11%, which was significantly higher than that of conventional ultrasound (74.81%; P<0.05).

Conclusions: CEUS can improve the accuracy rate of ultrasonography in the diagnosis and differential diagnosis of hyperechoic liver lesions.

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Figures

Figure 1
Figure 1
A 52-year-old man with HCC. (A) Gray-scale ultrasound shows a hyperechoic mass (arrow) in the right lobe of the liver. (B, C) Post-operative pathological examination revealed the well-differentiated hepatocellular carcinoma (solid type) with obvious hepatic fatty degeneration, hemorrhage, and necrosis. (D–F) CEUS image shows hypervascularity in the arterial phase and washout in the portal and late phase.
Figure 2
Figure 2
A 50-year-old man with cirrhotic nodules. (A) Gray-scale ultrasound shows a hyperechoic mass (arrow) in the right lobe of the liver. (B, C) Post-operative pathological examination revealed cirrhotic nodules. (D–F) CEUS image shows even enhancement in 3 phases.

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References

    1. Kim TK, Jang HJ. Contrast-enhanced ultrasound in the diagnosis of nodules in liver cirrhosis. World J Gastroenterol. 2014;20(13):3590–96. - PMC - PubMed
    1. Huang Y, Huang GJ. Application progress of contrast-enhanced ultrasound in diagnosis of focal liver lesions. Clin Ultras Med. 2013 [Epub ahead of print]
    1. Jiang YF, Zhou QC, Zhu CY. [Contrast-enhanced ultrasound in the diagnosis of benign and malignant hepatic tumors]. Centr Sou Univ (Med Sci) 2012;37(1):53–56. [in Chinese] - PubMed
    1. Luo W, Numata K, Kondo M, et al. Sonazoid-enhanced ultrasonography for evaluation of the enhancement patterns of focal liver tumors in the late phase by intermittent imaging with a high mechanical index. J Ultrasound Med. 2009;28(4):439–48. - PubMed
    1. Albrecht T, Blomley M, Bolondi L, et al. Guidelines for the use of contrast agents in ultrasound. January 2004. Ultraschall Med. 2004;25(4):249–56. - PubMed

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