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. 2015 Aug;11(5):603-10.
doi: 10.2217/whe.15.46. Epub 2015 Sep 23.

Serum markers for the noninvasive diagnosis of endometriosis

Stefano Luisi  1 , Serena Pinzauti  1 , Cristina Regini  1 , Felice Petraglia  1
Affiliations
Free article

Serum markers for the noninvasive diagnosis of endometriosis

Stefano Luisi et al. Womens Health (Lond). 2015 Aug.
Free article

Abstract

Endometriosis is a disease that affects millions of women worldwide and its diagnosis is still challenging. Medical history, symptoms together with imaging data may address the correct diagnosis, but the gold standard remains laparoscopic assessment with histological confirmation. The development of serum markers as diagnostic tools for endometriosis may allow a prompt and noninvasive diagnosis. Several serum biomarkers have been investigated over the years, but none of these have shown a clinical utility and nowadays the more realistic diagnostic biomarker consists in a panel of biomarkers. The recent introduction of new technologies such as genomics and proteomics may represent the future perspective of endometriosis diagnosis.

Keywords: CA-15.3; CA-19.9; activins; combined tests; cytokines; endometrioma; endometriosis; follistatin; serum markers; urocortin.

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