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. 2015 Aug;159(4):517-9.
doi: 10.1007/s10517-015-3006-6. Epub 2015 Sep 22.

Changes in the Mother-Placenta-Fetus System Under the Effect of α-Tocopherol in Albino Rats with Normal Pregnancy

A S Ivanova  1 , L P Peretyatko  2 , O G Sitnikova  2 , S B Nazarov  3   2
Affiliations

Changes in the Mother-Placenta-Fetus System Under the Effect of α-Tocopherol in Albino Rats with Normal Pregnancy

A S Ivanova et al. Bull Exp Biol Med. 2015 Aug.

Abstract

The effects of α-tocopherol on the function of the mother-placenta-fetus system and structural changes in the placenta in normal pregnancy were studied in albino rats. The results indicated that inhibition of free radical processes by injections of α-tocopherol in normal pregnancy led to disorders in the feto-maternal circulation, which was proven by morphological changes in the placenta. The disorders in the uteroplacental circulation manifested in the development of small-for-date fetuses and erythrocytosis.

Keywords: morphology; mother–placenta–fetus system; α-tocopherol.

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