Microsurgery and the Hypercoagulable State: A Hematologist's Perspective

Abstract

Hypercoagulability can pose a significant problem in microsurgical reconstruction. Here, the authors provide a comprehensive review of macrovascular and microvascular clotting phenomena from the unique viewpoint of two microsurgeons and a hematologist. The authors review the literature surrounding prevention of microvascular clots and provide an extensive discussion of hereditary thrombophilia. The authors also make explicit recommendations regarding the utility of thrombophilia testing and preoperative and perioperative management strategies for patients with hypercoagulability.