Liquisolid technology: What it can do for NSAIDs delivery?

Abstract

Liquisolid technology is also known as powder solution technology and is the technique which deals with the solubility term. This technology has been used to modify the dissolution rate of many drugs. Using this technique, many drugs exhibited enhanced or retarded dissolution rate. Non-steroidal anti-inflammatory drugs are among the highly important medications whose bioavailability is affected by the lower dissolution rate. In order to enhance the dissolution rate and subsequently the bioavailability of some of these drugs, liquisolid technology was used. This study reviewed the application of this useful technique for enhancing the dissolution rate of these important drugs and also the obtained results have been discussed in more details.

Keywords: Bioavailability; Dissolution rate; Liquisolid; NSAIDs.