Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Sep;3(9):767-8.
doi: 10.1002/ccr3.320. Epub 2015 Jul 29.

Clitoromegaly as first presentation of a neurocutaneous syndrome in a 3-year-old girl

Zacharoula Karabouta  1 , Israel Rousso  1 , Fani Athanassiadou-Piperopoulou  1
Affiliations

Clitoromegaly as first presentation of a neurocutaneous syndrome in a 3-year-old girl

Zacharoula Karabouta et al. Clin Case Rep. 2015 Sep.

Abstract

A rare cause of clitoral hypertrophy in a child is neurofibromatosis type 1 (NF1). Although evaluation, including karyotype and hormonal studies, is necessary to exclude ambiguous genitalia, the diagnosis of neurofibromatosis as a possible cause of clitoromegaly may help avoid lengthy and sometimes invasive interventions.

Keywords: Child; clitoromegaly; neurofibromatosis type 1.

PubMed Disclaimer

Figures

Figure 1
Figure 1
‘Café-au lait’ spots and clitoromegaly: signs of NF1 in the child.
Figure 2
Figure 2
MRI of external genitalia and brain, MRA of renal arteries.
See this image and copyright information in PMC

References

    1. Cost NG, Sanchez FS, Weinberg AG, Koral K. Baker LA. Neurofibromatosis presenting as painless clitoromegaly. Urol. J. 2009;6:220–222. - PubMed
    1. Duan L, Feng K, Tong A. Liang Z. Renal artery stenosis due to neurofibromatosis type 1: case report and literature review. Eur. J. Med. Res. 2014;19:17. - PMC - PubMed

LinkOut - more resources