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Comment
. 2015 Sep 23;87(6):1119-1121.
doi: 10.1016/j.neuron.2015.09.005.

How Do RIM-BPs Link Voltage-Gated Ca(2+) Channels to Evoked Neurotransmitter Release?

Ying C Li  1 , Ege T Kavalali  2
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How Do RIM-BPs Link Voltage-Gated Ca(2+) Channels to Evoked Neurotransmitter Release?

Ying C Li et al. Neuron. .
Free article

Abstract

Coupling between voltage-gated Ca(2+) influx and synaptic vesicle exocytosis is essential for rapid evoked neurotransmission. Acuna et al. show that the knockout of RIM-BPs, which are key structural components of this coupling, decreases the reliability of evoked neurotransmitter release.

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