Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Dec;4(4):376-80.
doi: 10.1093/jpids/piv032. Epub 2015 May 28.

A Toddler With Rash, Encephalopathy, and Hemolytic Anemia

Affiliations
Case Reports

A Toddler With Rash, Encephalopathy, and Hemolytic Anemia

Christiana Smith et al. J Pediatric Infect Dis Soc. 2015 Dec.
No abstract available

Keywords: Oka strain; RAG; SCID; VZV; Varicella; immunodeficiency.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Rash consisting of discrete crusted lesions on the trunk.
Figure 2.
Figure 2.
Rash consisting of “punched-out” ulcerated lesions on the genitalia.
Figure 3.
Figure 3.
Magnetic resonance image of the brain with symmetric increased T2 signal involving the dorsal medulla and upper cervical spinal cord.
Figure 4.
Figure 4.
Post mortem examination of lymph nodes revealing moderate to severe lymphoid depletion with absent follicular architecture. Hematoxylin and eosin stain, 100×.
Figure 5.
Figure 5.
Post mortem examination of the lungs demonstrating multifocal scar-like plaques.
Figure 6.
Figure 6.
Post mortem examination of the lungs displaying multinucleated giant cells typical of varicella-zoster virus lesions. Hematoxylin and eosin stain, 100×.

Similar articles

Cited by

References

    1. Weinmann S, Chun C, Schmid DS, et al. Incidence and clinical characteristics of herpes zoster among children in the varicella vaccine era, 2005–2009. J Infect Dis 2013; 208:1859–68. - PubMed
    1. Galea SA, Sweet A, Beninger P, et al. The safety profile of varicella vaccine: a 10-year review. J Infect Dis 2008; 197 (Suppl 2):S165–9. - PubMed
    1. Iyer S, Mittal MK, Hodinka RL. Herpes zoster and meningitis resulting from reactivation of varicella vaccine virus in an immunocompetent child. Ann Emerg Med 2009; 53:792–5. - PubMed
    1. Chouliaras G, Spoulou V, Quinlivan M, et al. Vaccine-associated herpes zoster ophthalmicus and encephalitis in an immunocompetent child. Pediatrics 2010; 125:e969–72. - PubMed
    1. Levin MJ, DeBiasi RL, Bostik V, Schmid DS. Herpes zoster with skin lesions and meningitis caused by 2 different genotypes of the Oka varicella-zoster virus vaccine. J Infect Dis 2008; 198:1444–7. - PubMed

Publication types