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. 2016 Jun;5(2):227-30.
doi: 10.1093/jpids/piv059. Epub 2015 Sep 9.

Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality

Huynh T Trieu  1 , Inke N Lubis  2 , Phan T Qui  1 , Lam M Yen  1 , Bridget Wills  3 , C Louise Thwaites  3 , Saraswathy Sabanathan  3
Affiliations

Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality

Huynh T Trieu et al. J Pediatric Infect Dis Soc. 2016 Jun.

Abstract

We report a 66% reduction in neonatal tetanus mortality after introducing a new management bundle integrating antibiotic therapy, muscle relaxation and invasive monitoring. The latter allowed rapid detection of autonomic instability which was treated with magnesium sulphate. This is the first report of its use in neonatal tetanus.

Keywords: autonomic dysfunction; magnesium sulfate; neonatal tetanus.

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References

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