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. 2015 Oct 15;61Suppl 3(Suppl 3):S155-9.
doi: 10.1093/cid/civ611.

RePORT International: Advancing Tuberculosis Biomarker Research Through Global Collaboration

Carol D Hamilton  1 , Soumya Swaminathan  2 , Devasahayam J Christopher  3 , Jerrold Ellner  4 , Amita Gupta  5 , Timothy R Sterling  6 , Valeria Rolla  7 , Sudha Srinivasan  8 , Muhammad Karyana  9 , Sophia Siddiqui  10 , Sonia K Stoszek  11 , Peter Kim  8
Affiliations

RePORT International: Advancing Tuberculosis Biomarker Research Through Global Collaboration

Carol D Hamilton et al. Clin Infect Dis. .

Abstract

Progress in tuberculosis clinical research is hampered by a lack of reliable biomarkers that predict progression from latent to active tuberculosis, and subsequent cure, relapse, or failure. Regional Prospective Observational Research in Tuberculosis (RePORT) International represents a consortium of regional cohorts (RePORT India, RePORT Brazil, and RePORT Indonesia) that are linked through the implementation of a Common Protocol for data and specimen collection, and are poised to address this critical research need. Each RePORT network is designed to support local, in-country tuberculosis-specific data and specimen biorepositories, and associated research. Taken together, the expected results include greater global clinical research capacity in high-burden settings, and increased local access to quality data and specimens for members of each network and their domestic and international collaborators. Additional networks are expected to be added, helping to spur tuberculosis treatment and prevention research around the world.

Keywords: biological markers; biological specimen banks; prospective studies; specimen handling; tuberculosis.

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