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Review
. 2015 Oct:16 Suppl 1:6-8.
doi: 10.1016/j.prrv.2015.07.007. Epub 2015 Sep 26.

Induced sputum in young healthy children with cystic fibrosis

Julian Forton  1
Affiliations
Review

Induced sputum in young healthy children with cystic fibrosis

Julian Forton. Paediatr Respir Rev. 2015 Oct.

Abstract

Young children with CF are often asymptomatic and non-productive, yet CF lung disease occurs early in life. Cough swabs are used routinely to sample bacteria from the CF respiratory tract in non-productive healthy children; bronchoscopy is used to definitively sample the lower airway, but is an invasive procedure. Induced sputum is a non-invasive approach to sampling the lower airway. The article concentrates on how well it is tolerated in children, how successful it is in identifying respiratory pathogens, and how it may be important in routine surveillance if 16S technology is to be used in the clinical forum.

Keywords: Children; Cystic Fibrosis; Induced sputum; Respiratory microbiome.

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