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Case Reports
. 2015 Dec;262(12):2676-7.
doi: 10.1007/s00415-015-7897-y. Epub 2015 Sep 26.

Rituximab is effective in severe treatment-resistant neurological Behçet's syndrome

D P Kidd  1   2
Affiliations
Case Reports

Rituximab is effective in severe treatment-resistant neurological Behçet's syndrome

D P Kidd. J Neurol. 2015 Dec.

Abstract

The objective of this study is to describe a case of severe and treatment-resistant neurological Behçet's syndrome responsive to a novel therapy. This case report describes the patient who failed to respond to conventional therapy but the brain stem lesion resolved with the anti-CD20 biological agent rituximab. Neurological complications are uncommon in Behçet's syndrome; 80% involve a meningoencephalitis which can be severe and relapsing. This is the first report of effectiveness of rituximab in this uncommon disease.

Keywords: Behçet’s syndrome; Neurological; Rituximab; Treatment.

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References

    1. Arthritis Rheum. 2008 Feb 15;59(2):285-90 - PubMed
    1. Mod Rheumatol. 2008;18(3):306-8 - PubMed
    1. Semin Arthritis Rheum. 2011 Aug;41(1):61-70 - PubMed
    1. Lancet Neurol. 2009 Feb;8(2):192-204 - PubMed
    1. Mediators Inflamm. 2014;2014:107421 - PubMed

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