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. 2015 Oct;26(10):512-514.
doi: 10.1016/j.tem.2015.07.010.

Insulin-Mediated Diseases: Adrenal Mass and Polycystic Ovary Syndrome

Giovanna Muscogiuri  1 , Annamaria Colao  2 , Francesco Orio  3
Affiliations

Insulin-Mediated Diseases: Adrenal Mass and Polycystic Ovary Syndrome

Giovanna Muscogiuri et al. Trends Endocrinol Metab. 2015 Oct.

Abstract

Adrenal incidentalomas (AIs) and polycystic ovary syndrome (PCOS) have often been associated with compensatory hyperinsulinemia and insulin resistance (IR). The link between these diseases and IR may be changes in hormone secretions that provoke IR and in turn promote the growth of adrenal gland masses and/or ovarian cysts through compensatory hyperinsulinemia.

Keywords: PCOS; Type 2 diabetes; adrenal incidentaloma; insulin resistance.

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