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. 2016 Apr;41(3):373-83.
doi: 10.1093/jpepsy/jsv092. Epub 2015 Sep 27.

Predicting Later Study Withdrawal in Participants Active in a Longitudinal Birth Cohort Study for 1 Year: The TEDDY Study

Suzanne Bennett Johnson  1 , Kristian F Lynch  2 , Judith Baxter  3 , Barbro Lernmark  4 , Roswith Roth  5 , Tuula Simell  6 , Laura Smith  2 ; TEDDY Study Group
Affiliations

Predicting Later Study Withdrawal in Participants Active in a Longitudinal Birth Cohort Study for 1 Year: The TEDDY Study

Suzanne Bennett Johnson et al. J Pediatr Psychol. 2016 Apr.

Abstract

Objective: To identify predictors of later study withdrawal among participants active in The Environmental Determinants of Diabetes in the Young (TEDDY) for 1 year.

Methods: Multiple logistic regression was used to discriminate 3,042 children active in TEDDY for the first 3 years from 432 children who withdrew in Years 2 or 3. Predictor variables were tested in blocks-demographic, maternal lifestyle behaviors, stress and child illness, maternal reactions to child's increased diabetes risk, in-study behaviors-and a final best model developed.

Results: Few demographic factors predicted study withdrawal. Maternal lifestyle behaviors, accuracy of the mother's risk perception, and in-study behaviors were more important. Frequent child illnesses were associated with greater study retention.

Conclusions: Demographic measures are insufficient predictors of later study withdrawal among those active in a study for at least 1 year; behavioral/psychological factors offer improved prediction and guidance for the development of retention strategies.

Keywords: adherence; diabetes; genetics and genetic disorders; longitudinal research; prevention/control; research design and methods.

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Figures

Figure 1.
Figure 1.
ROC curves for null, demographics only, and final model.
See this image and copyright information in PMC

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