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Review
. 2015 Sep 28;7(21):2336-43.
doi: 10.4254/wjh.v7.i21.2336.

Renal failure in cirrhosis: Emerging concepts

Paulo Lisboa Bittencourt  1 , Alberto Queiroz Farias  1 , Carlos Terra  1
Affiliations
Review

Renal failure in cirrhosis: Emerging concepts

Paulo Lisboa Bittencourt et al. World J Hepatol. .

Abstract

Acute renal failure, now termed acute kidney injury (AKI), is frequently found in patients with cirrhosis. The occurrence of AKI, irrespective of the underlying cause, is associated with reduced in-hospital, 3-mo and 1-year survival. Hepatorenal syndrome is associated with the worst outcome among AKI patients with cirrhosis. Several definitions for AKI that have been proposed are outlined and evaluated in this paper. Among these, the International Club for Ascites-AKI criteria substantially strengthen the quality of early diagnosis and intervention according to underlying cause of AKI.

Keywords: Acute kidney injury; End-stage liver disease; Hepatorenal syndrome; Liver cirrhosis; Renal failure.

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