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Review
. 2015 Sep 29:14:121.
doi: 10.1186/s12944-015-0123-1.

The role of fatty acids in insulin resistance

Barry Sears  1 , Mary Perry  2
Affiliations
Review

The role of fatty acids in insulin resistance

Barry Sears et al. Lipids Health Dis. .

Abstract

Insulin resistance is a multi-faceted disruption of the communication between insulin and the interior of a target cell. The underlying cause of insulin appears to be inflammation that can either be increased or decreased by the fatty acid composition of the diet. However, the molecular basis for insulin resistance can be quite different in various organs. This review deals with various types of inflammatory inputs mediated by fatty acids, which affect the extent of insulin resistance in various organs.

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Figures

Fig. 1
Fig. 1
Organs affected by fatty acid-mediated insulin resistance
See this image and copyright information in PMC

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