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. 2015 Dec;93(6):1311-7.
doi: 10.4269/ajtmh.15-0467. Epub 2015 Sep 28.

Predictive Value of School-Aged Children's Schistosomiasis Prevalence and Egg Intensity for Other Age Groups in Western Kenya

Pauline N M Mwinzi  1 , Geoffrey Muchiri  1 , Ryan E Wiegand  1 , Martin Omedo  1 , Bernard Abudho  1 , Diana M S Karanja  1 , Susan P Montgomery  1 , W Evan Secor  2
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Predictive Value of School-Aged Children's Schistosomiasis Prevalence and Egg Intensity for Other Age Groups in Western Kenya

Pauline N M Mwinzi et al. Am J Trop Med Hyg. 2015 Dec.

Abstract

World Health Organization recommendations for the timing and target population for mass drug administration (MDA) for schistosomiasis are based on the prevalence of infection in school children within a given community. In a large study comparing MDA approaches for Schistosoma mansoni control, we evaluated whether prevalence of infection and egg burdens in 9- to 12-year-old students reflected infection levels in young children and adults in the same community. Cross-sectional surveys of preadolescents (9-12 years old) were compared with those of first year students (5-8 years old) in 225 villages and adults (20-55 years old) in 150 villages along the Kenyan shores of Lake Victoria. Village schistosomiasis prevalence and intensity levels in preadolescents strongly correlated (P < 0.0001) with prevalence and infection intensity for other age groups in the community. Our findings suggest that S. mansoni prevalence and intensity among 9- to 12-year-olds are valid for community sampling purposes in mapping for MDAs.

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Figures

Figure 1.
Figure 1.
Relationship between prevalence of infection and intensity of infection as expressed by geometric mean eggs per gram feces + 1. Village-level estimates are weighted by the sample size, where villages with a sample size ≥ 20 receive a weight of one and village with a sample size < 20 receive a weight of the sample size divided by 20. Each dot represents one village with the size of the dot proportional to the number of participants in that village. The legend provides examples of symbol size for a given number of village participants.
Figure 2.
Figure 2.
Relationships between prevalence of infection in 9- to 12-year-olds and other age groups. Village-level estimates are weighted by the sample size, where villages with a sample size ≥ 20 receive a weight of one and village with a sample size < 20 receive a weight of the sample size divided by 20. Each dot represents one village with the size of the dot proportional to the number of participants in that village. The legend provides examples of symbol size for a given number of village participants.
Figure 3.
Figure 3.
Relationship between intensity of infection in 9- to 12-year-olds as expressed by geometric mean eggs per gram feces + 1 and the other age groups. Village-level estimates are weighted by the sample size, where villages with a sample size ≥ 20 receive a weight of one and village with a sample size < 20 receive a weight of the sample size divided by 20. Each dot represents one village with the size of the dot proportional to the number of participants in that village. The legend provides examples of symbol size for a given number of village participants.
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References

    1. Montresor A, Crompton DWT, Hall A, Bundy DAP, Savioli L. Guidelines for the Evaluation of Soil-Transmitted Helminthiasis and Schistosomiasis at Community Level. Geneva, Switzerland: World Health Organization; 1998.
    1. Savioli L, Stansfield S, Bundy DA, Mitchell A, Bhatia R, Engels D, Montresor A, Neira M, Shein AM. Schistosomiasis and soil-transmitted helminth infections: forging control efforts. Trans R Soc Trop Med Hyg. 2002;96:577–579. - PMC - PubMed
    1. World Health Organization . Prevention and Control of Schistosomiasis and Soil-Transmitted Helminthiasis. Geneva, Switzerland: World Health Organization; 2002. http://whqlibdoc.who.int/trs/WHO_TRS_912.pdf (Report of a WHO Expert Committee). Available at. Accessed April 3, 2013. - PubMed
    1. World Health Organization . Report of an Informal Consultation on Schistosomiasis Control. Geneva, Switzerland: World Health Organization; 2011. www.who.int/iris/bitstream/10665/78066/1/9789241505017_eng.pdf Available at. Accessed April 3, 2013.
    1. World Health Organization . Preventive Chemotherapy in Human Helminthiasis. Geneva, Switzerland: World Health Organization; 2006. http://whqlibdoc.who.int/publications/2006/9241547103_eng.pdf Available at. Accessed April 3, 2013.

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