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Review
. 2015 Sep 13:14:105-7.
doi: 10.4137/CIN.S26470. eCollection 2015.

Alview: Portable Software for Viewing Sequence Reads in BAM Formatted Files

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Review

Alview: Portable Software for Viewing Sequence Reads in BAM Formatted Files

Richard P Finney et al. Cancer Inform. .

Abstract

The name Alview is a contraction of the term Alignment Viewer. Alview is a compiled to native architecture software tool for visualizing the alignment of sequencing data. Inputs are files of short-read sequences aligned to a reference genome in the SAM/BAM format and files containing reference genome data. Outputs are visualizations of these aligned short reads. Alview is written in portable C with optional graphical user interface (GUI) code written in C, C++, and Objective-C. The application can run in three different ways: as a web server, as a command line tool, or as a native, GUI program. Alview is compatible with Microsoft Windows, Linux, and Apple OS X. It is available as a web demo at https://cgwb.nci.nih.gov/cgi-bin/alview. The source code and Windows/Mac/Linux executables are available via https://github.com/NCIP/alview.

Keywords: BAM; alignment; genomics; open source; short read; visualization.

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Figures

Figure 1
Figure 1
Information and navigation in Alview – upper left is original and lower right is zoom in via mouse drag to examine SNP. Various navigation buttons and information blocks assist in browsing BAM files.

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