Integrated spatiotemporal-metabolic modelling bridges the gap between metabolism on the cellular level and organ function
- PMID: 26417345
- PMCID: PMC4464484
Integrated spatiotemporal-metabolic modelling bridges the gap between metabolism on the cellular level and organ function
References
-
- Doktorova TY, Ellinger-Ziegelbauer H, Vinken M, Vanhaecke T, van Delft J, Kleinjans J, et al. Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data. Arch Toxicol. 2012;86:1703–1715. - PubMed
-
- Doktorova TY, Ellinger-Ziegelbauer H, Vinken M, Vanhaecke T, van Delft J, Kleinjans J, et al. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver. Arch Toxicol. 2012;86:1399–1411. - PubMed
-
- Drasdo D, Hoehme S, Hengstler JG. How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis. J Hepatol. 2014;61:951–956. - PubMed
-
- Fernandes E, Carvalho M, Carvalho F, Silva AM, Santos CM, Pinto DC, et al. Hepatoprotective activity of polyhydroxylated 2-styrylchromones against tert-butylhydroperoxide induced toxicity in freshly isolated rat hepatocytes. Arch Toxicol. 2003;77:500–505. - PubMed
-
- Fraczek J, Bolleyn J, Vanhaecke T, Rogiers V, Vinken M. Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies. Arch Toxicol. 2013;87:577–610. - PubMed
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