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. 2015 Aug 19;6(9):3431-6.
doi: 10.1364/BOE.6.003431. eCollection 2015 Sep 1.

Bedside monitoring of patients with shock using a portable spatially-resolved near-infrared spectroscopy

Ting Li  1 , Meixue Duan  2 , Kai Li  3 , Guoqiang Yu  4 , Zhengshang Ruan  5
Affiliations

Bedside monitoring of patients with shock using a portable spatially-resolved near-infrared spectroscopy

Ting Li et al. Biomed Opt Express. .

Abstract

Clinical monitoring of shock mainly depends on blood-oxygen-indices obtained from invasive blood sample tests. The central internal jugular central vein oxygenation level (ScvO2) has been considered as a gold standard indicator for shock prediction. We developed a noninvasive spatially-resolved near-infrared spectroscopy (SR-NIRS) to measure tissue blood oxygen saturation (StO2) surrounding the region of taking blood sample for the ScvO2 test in 25 patients with shock. StO2 values were found to be highly correlated (r = 0.84, p < 0.001) with ScvO2 levels and the concordance coefficient of 0.80 is high. The results suggest the potential of noninvasive SR-NIRS for bedside shock monitoring.

Keywords: (170.1470) Blood or tissue constituent monitoring; (300.0300) Spectroscopy.

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Figures

Fig. 1
Fig. 1
Portable spatially-resolved near-infrared spectroscopy (SR-NIRS) device for bedside shock monitoring. (a) SR-NIRS probe placement; (b) SR-NIRS shock monitor device; (c) Bedside shock monitoring.
Fig. 2
Fig. 2
(a) Ultrasonograph of internal jugular central vein and (b) Monte Carlo simulation of photon paths within the tissues surrounding the veins.
Fig. 3
Fig. 3
The correlations between StO2 and conventional blood oxygen indices, represented by scatter plot with least-squares fitted lines added.
Fig. 4
Fig. 4
NIRS-measured StO2 compared to the gold standard ScvO2 from the blood sample test. (a) The solid line represents the best fit to the data; the dashed line indicates the perfect equivalent; and the dot line denotes the 95% confidence interval for StO2. (b) Bland-Altman plot of the deference between the StO2 and ScvO2 as well as the mean difference (solid horizontal line) between these two parameters. The dash lines indicate the 95% limits of an agreement.
See this image and copyright information in PMC

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