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Comment
. 2015 Oct;47(10):1102-3.
doi: 10.1038/ng.3408.

Gene signatures from pancreatic cancer tumor and stromal cells predict disease outcome

Filippos Kottakis  1 , Nabeel Bardeesy  1
Affiliations
Comment

Gene signatures from pancreatic cancer tumor and stromal cells predict disease outcome

Filippos Kottakis et al. Nat Genet. 2015 Oct.

Abstract

Pancreatic cancers consist of a heterogeneous amalgam of assorted cell types, making it challenging to develop a classification system that groups these tumors according to common molecular features. A new study tackles this important issue using bioinformatics approaches to decipher gene expression signatures derived specifically from either tumor cells or nonmalignant stromal cells that predict patient outcome and may inform personalized treatments.

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References

    1. Nature. 2010 Oct 28;467(7319):1109-13 - PubMed
    1. Cancer Cell. 2012 Mar 20;21(3):418-29 - PubMed
    1. Cell. 2014 Apr 24;157(3):580-94 - PubMed
    1. Cancer Cell. 2014 Jun 16;25(6):735-47 - PubMed
    1. Nature. 2010 Oct 28;467(7319):1114-7 - PubMed

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