Further support for the association of GNPAT variant rs11558492 with severe iron overload in hemochromatosis

Affiliations

¹ Inserm U1043, Toulouse, France.
² Department of Hepato-Gastroenterology, CHU de Toulouse, Hôpital Purpan, Toulouse, France.
³ Laboratory of Hematology, CHRU de Montpellier, Hôpital Saint Eloi, Montpellier, France.

Comment

Céline Besson-Fournier et al. Hepatology. 2016 Jun.

. 2016 Jun;63(6):2054-5.

doi: 10.1002/hep.28259. Epub 2015 Oct 30.

¹ Inserm U1043, Toulouse, France.
² Department of Hepato-Gastroenterology, CHU de Toulouse, Hôpital Purpan, Toulouse, France.
³ Laboratory of Hematology, CHRU de Montpellier, Hôpital Saint Eloi, Montpellier, France.

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McLaren CE, Barton JC, Phatak PD, Emond MJ, Subramaniam VN, Gurrin LC, Adams PC, Powell LW, Ramm GA, Anderson GJ, McLaren GD. McLaren CE, et al. Hepatology. 2016 Jun;63(6):2056-7. doi: 10.1002/hep.28260. Epub 2015 Dec 18. Hepatology. 2016. PMID: 26417986 Free PMC article. No abstract available.

Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload.
McLaren CE, Emond MJ, Subramaniam VN, Phatak PD, Barton JC, Adams PC, Goh JB, McDonald CJ, Powell LW, Gurrin LC, Allen KJ, Nickerson DA, Louie T, Ramm GA, Anderson GJ, McLaren GD. McLaren CE, et al. Hepatology. 2015 Aug;62(2):429-39. doi: 10.1002/hep.27711. Epub 2015 Mar 18. Hepatology. 2015. PMID: 25605615 Free PMC article.