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Review
. 2015 Sep 25;7(13):1088-95.
doi: 10.4253/wjge.v7.i13.1088.

Upper non-variceal gastrointestinal bleeding - review the effectiveness of endoscopic hemostasis methods

Mirosław Szura  1 , Artur Pasternak  1
Affiliations
Review

Upper non-variceal gastrointestinal bleeding - review the effectiveness of endoscopic hemostasis methods

Mirosław Szura et al. World J Gastrointest Endosc. .

Abstract

Upper non-variceal gastrointestinal bleeding is a condition that requires immediate medical intervention and has a high associated mortality rate (exceeding 10%). The vast majority of upper gastrointestinal bleeding cases are due to peptic ulcers. Helicobacter pylori infection, non-steroidal anti-inflammatory drugs and aspirin are the main risk factors for peptic ulcer disease. Endoscopic therapy has generally been recommended as the first-line treatment for upper gastrointestinal bleeding as it has been shown to reduce recurrent bleeding, the need for surgery and mortality. Early endoscopy (within 24 h of hospital admission) has a greater impact than delayed endoscopy on the length of hospital stay and requirement for blood transfusion. This paper aims to review and compare the efficacy of the types of endoscopic hemostasis most commonly used to control non-variceal gastrointestinal bleeding by pooling data from the literature.

Keywords: Endoscopic hemostasis; Endoscopic therapy; Non-variceal bleeding; Upper gastrointestinal bleeding.

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Figures

Figure 1
Figure 1
Endoscopic clips.
Figure 2
Figure 2
Endoscopic band ligation.
Figure 3
Figure 3
Argon plasma coagulation.
See this image and copyright information in PMC

References

    1. Chak A, Cooper GS, Lloyd LE, Kolz CS, Barnhart BA, Wong RC. Effectiveness of endoscopy in patients admitted to the intensive care unit with upper GI hemorrhage. Gastrointest Endosc. 2001;53:6–13. - PubMed
    1. Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, Sinclair P; International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010;152:101–113. - PubMed
    1. Rockall TA, Logan RF, Devlin HB, Northfield TC. Incidence of and mortality from acute upper gastrointestinal haemorrhage in the United Kingdom. Steering Committee and members of the National Audit of Acute Upper Gastrointestinal Haemorrhage. BMJ. 1995;311:222–226. - PMC - PubMed
    1. van Leerdam ME, Vreeburg EM, Rauws EA, Geraedts AA, Tijssen JG, Reitsma JB, Tytgat GN. Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000. Am J Gastroenterol. 2003;98:1494–1499. - PubMed
    1. Gilbert DA. Epidemiology of upper gastrointestinal bleeding. Gastrointest Endosc. 1990;36:S8–13. - PubMed

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