A case study of human immunodeficiency virus with positive seroconversion to negative
- PMID: 26425294
- PMCID: PMC4567892
A case study of human immunodeficiency virus with positive seroconversion to negative
Abstract
This case study demonstrates a 36-year-old ex-intravenous drug user (IVDU) who had been initially tested positive for human immunodeficiency virus (HIV) twice using Enzyme Immunoassay (EIA) method (Particle agglutination, PA done), but a year later he was tested HIV-negative. The patient was asymptomatic for HIV and T helper cells (CD4) count remained stable throughout this period. In light of this case, there may be a need to retest by molecular methods for high risk category patients who were initially diagnosed HIV-positive, but later showing an unexpected clinical course, such as a rising or stable CD4 titre over the years.
Keywords: HIV testing; false-positive; seroconversion.
References
-
- Lewin SR, Rouzioux C. HIV cure and eradication: How will we get from the laboratory to effective clinical trials? AIDS. 2011;25:885–97. - PubMed
-
- UNAIDS/WHO. Guidelines for using HIV testing technologies in Surveillance: Selection, evaluation and implementation. Geneva: UNAIDS/WHO; 2009 update. - PubMed
-
- Insert Package of HIV testing in laboratory (AxSym HIV 1/2 G.O test), Abbott Laboratories, Ref 3D41-22, April 2009.
-
- Poljak M, Zener N, Seme K. et al. Particle agglutination test “Serodia HIV-1/2” as a novel anti-HIV-1/2 screening test: Comparative study on 3311 serum samples. Folia Biol (Praha) 1997;43(4):171–3. - PubMed
-
- Brun-Vezinet F, Simon F. Diagnostic tests for HIV infection. Armstrong D, Cohen J, editors. Infectious Diseases. 1999:1–10. London: Mosby.
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