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Case Reports
. 2015 May 19:13:20-2.
doi: 10.1016/j.gore.2015.05.001. eCollection 2015 Aug.

Solitary ovarian plasmacytoma. A case report and review of literature

Aharon Feldman  1 , Derek Isrow  1 , Daniel Schultz  2 , Kedar Inamdar  2 , Nabila Rasool  3 , Mohamed A Elshaikh  1
Affiliations
Case Reports

Solitary ovarian plasmacytoma. A case report and review of literature

Aharon Feldman et al. Gynecol Oncol Rep. .

Abstract

•A patient with rare solitary ovarian plasmacytoma is reported•Diagnostic work-up is mandatory to rule out ovarian involvement as part of multiple myeloma.•After complete surgical resection, the prognosis appears to be very favorable.

Keywords: Extramedullary plasmacytoma; Multiple myeloma; Ovarian Neoplasms; Plasma cell dyscrasia; Plasmacytoma.

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Figures

Fig. 1
Fig. 1
Macroscopic examination shows a 14 cm, 597 g ovary with smooth capsule that is focally calcified; cut surface shows multiple cysts with myxoid, rubbery and hemorrhagic septa and contents.
Fig. 2
Fig. 2
Microscopic H&E with (a) medium high (× 20) and (b) high power (× 40) shows mostly mature plasma cells with eccentric clock-faced nuclei and infrequent mitoses; no admixed lymphocytes.
Fig. 3
Fig. 3
Special stains using in-situ hybridization (ISH) showing Kappa positive (in blue) (a), Lambda negative (b) and immunohistologic stain positive for CD138 (in brown) (c).
See this image and copyright information in PMC

References

    1. Alexiou C., Kau R.J., Dietzfelbinger H., Kremer M., Spiess J.C., Schratzenstaller B. Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts. Cancer. 1999;85(11):2305–2314. - PubMed
    1. Anderson K., Alsina M., Bensinger W., Biermann J., Chanan-Khan A., Cohen A. Multiple myeloma: clinical practice guidelines in oncology. JNCCN. 2011;9:1146–1183. - PubMed
    1. Bambirra E.A., Miranda D., Magalhaes G.M.C. Plasma cell myeloma simulating Krukenberg's tumor. South. Med. J. 1982;75:511–512. - PubMed
    1. Cook H.T., Boylston A.W. Plasmacytoma of the ovary. Gynecol. Oncol. 1988;29:378–381. - PubMed
    1. Dagan R., Morris C.G., Kirwan J., Mendenhall W.M. Solitary plasmacytoma. Am. J. Clin. Oncol. 2009;32:612–617. - PubMed

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