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Review
. 1989 Jan;39(1):111-8.
doi: 10.1212/wnl.39.1.111.

Hypoxic neuropathy: does hypoxia play a role in diabetic neuropathy? The 1988 Robert Wartenberg lecture

P J Dyck  1
Affiliations
Review

Hypoxic neuropathy: does hypoxia play a role in diabetic neuropathy? The 1988 Robert Wartenberg lecture

P J Dyck. Neurology. 1989 Jan.

Abstract

In this report I review: (1) the blood supply and endoneurial microenvironment of nerve; (2) the class, type, and spatial distribution of nerve fiber degeneration as a function of number, site, and class of vessels occluded; (3) the putative mechanisms of nerve hypoxia; and (4) the role of hypoxia in diabetic polyneuropathy.

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