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Randomized Controlled Trial
. 2015 Oct 1:15:232.
doi: 10.1186/s12888-015-0602-y.

Problem Management Plus (PM+) for common mental disorders in a humanitarian setting in Pakistan; study protocol for a randomised controlled trial (RCT)

Marit Sijbrandij  1 , Saeed Farooq  2 , Richard A Bryant  3 , Katie Dawson  4 , Syed Usman Hamdani  5 , Anna Chiumento  6 , Fareed Minhas  7 , Khalid Saeed  8 , Atif Rahman  9 , Mark van Ommeren  10
Affiliations
Randomized Controlled Trial

Problem Management Plus (PM+) for common mental disorders in a humanitarian setting in Pakistan; study protocol for a randomised controlled trial (RCT)

Marit Sijbrandij et al. BMC Psychiatry. .

Erratum in

Abstract

Background: In humanitarian settings common mental disorders (depression, anxiety disorders, posttraumatic stress disorder) are highly prevalent. The World Health Organization (WHO) has developed Problem Management Plus (PM+), a 5-session, individual psychological intervention program, delivered by paraprofessionals that addresses common mental disorders in people in communities affected by adversity. The objectives of this study are to test effectiveness and cost-effectiveness of the locally adapted PM+ compared to Treatment as usual (TAU) in Peshawar District, Pakistan.

Methods: A randomised controlled trial will be conducted in 346 primary care attendees in 3 health care centres in Peshawar District, Pakistan. After informed consent, primary care attendees with high levels of psychological distress according to the General Health Questionnaire-12 (GHQ-12) and functional impairment (WHO Disability Assessment Schedule 2.0 (WHODAS)) will be assigned to PM+ (n = 173) or TAU (n = 173). At baseline, 1 week and 3 months following PM+, independent assessors will assess psychological distress with the Hospital Anxiety and Depression Scale (HADS), and functional disability with the WHODAS. Secondary outcomes are posttraumatic stress disorder (PTSD) symptoms, and client-perceived priority problems. Further, cost-effectiveness will be assessed using the Service Receipt Inventory (SRI).

Discussion: If proven effective, PM+ will be rolled out to other areas for further adaptation and testing in diverse humanitarian settings.

Trial registration: ACTRN12614001235695. Registered 26 November 2014. Australian New Zealand Clinical Trials Registry.

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References

    1. Khalily MT. Mental health problems in Pakistani society as a consequence of violence and trauma: a case for better integration of care. Int J Integ Care. 2011;11 - PMC - PubMed
    1. Tol WA, Barbui C, Galappatti A, Silove D, Betancourt TS, Souza R, et al. Mental health and psychosocial support in humanitarian settings: linking practice and research. Lancet. 2011;378(9802):1581–1591. doi: 10.1016/S0140-6736(11)61094-5. - DOI - PMC - PubMed
    1. Jafar TH, Haaland BA, Rahman A, Razzak JA, Bilger M, Naghavi M, et al. Non-communicable diseases and injuries in Pakistan: strategic priorities. Lancet. 2013;381(9885):2281–2290. doi: 10.1016/S0140-6736(13)60646-7. - DOI - PubMed
    1. Whiteford HA, Degenhardt L, Rehm J, Ferrari AJ, Feigin V, Vos T, et al. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet. 2013;382(9904):1575–1586. doi: 10.1016/S0140-6736(13)61611-6. - DOI - PubMed
    1. Kohn R, Saxena S, Levav I, Saraceno B. The treatment gap in mental health care. Bull World Health Organ. 2004;82(11):858–866. - PMC - PubMed

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