How's your microbiota? Let's check your urine
- PMID: 26429966
- DOI: 10.1182/blood-2015-08-661504
How's your microbiota? Let's check your urine
Abstract
In this issue of Blood, Weber and colleagues demonstrate that in the first 10 days following allogeneic hematopoietic transplantation, urinary 3-indoxyl sulfate is a biomarker of intestinal microbiota health and predicts reduced intestinal graft-versus-host disease (GVHD) and treatment-related mortality, as well as improved overall survival.
Comment on
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Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome.Blood. 2015 Oct 1;126(14):1723-8. doi: 10.1182/blood-2015-04-638858. Epub 2015 Jul 24. Blood. 2015. PMID: 26209659
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