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. 2015 Oct 1;3(5):e01106-15.
doi: 10.1128/genomeA.01106-15.

Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism

Hannes Horn  1 , Ute Hentschel  1 , Usama Ramadan Abdelmohsen  2
Affiliations

Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism

Hannes Horn et al. Genome Announc. .

Abstract

Here, we report the draft genome sequences of three actinobacterial isolates, Micromonospora sp. RV43, Rubrobacter sp. RV113, and Nocardiopsis sp. RV163 that had previously been isolated from Mediterranean sponges. The draft genomes were analyzed for the presence of gene clusters indicative of secondary metabolism using antiSMASH 3.0 and NapDos pipelines. Our findings demonstrated the chemical richness of sponge-associated actinomycetes and the efficacy of genome mining in exploring the genomic potential of sponge-derived actinomycetes.

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