Better Safe than Sorry: Interlinked Feedback Loops for Robust Mitophagy

Andrew G Manford¹, Michael Rape²

Affiliations

¹ Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
² Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. Electronic address: mrape@berkeley.edu.

PMID: 26431022
DOI: 10.1016/j.molcel.2015.09.016

Free article

Comment

Better Safe than Sorry: Interlinked Feedback Loops for Robust Mitophagy

Andrew G Manford et al. Mol Cell. 2015.

Free article

. 2015 Oct 1;60(1):1-2.

doi: 10.1016/j.molcel.2015.09.016.

Authors

Andrew G Manford¹, Michael Rape²

Affiliations

¹ Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
² Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. Electronic address: mrape@berkeley.edu.

PMID: 26431022
DOI: 10.1016/j.molcel.2015.09.016

Abstract

In this issue of Molecular Cell, Heo et al. (2015) uncover a new mechanism of signal amplification during mitophagy through cooperative regulation of the TBK1 kinase and autophagy receptors.

PubMed Disclaimer

Comment on

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
Heo JM, Ordureau A, Paulo JA, Rinehart J, Harper JW. Heo JM, et al. Mol Cell. 2015 Oct 1;60(1):7-20. doi: 10.1016/j.molcel.2015.08.016. Epub 2015 Sep 10. Mol Cell. 2015. PMID: 26365381 Free PMC article.

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions

Grants and funding

Howard Hughes Medical Institute/United States

LinkOut - more resources

Full Text Sources
- Elsevier Science
Miscellaneous
- NCI CPTAC Assay Portal

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Better Safe than Sorry: Interlinked Feedback Loops for Robust Mitophagy

Affiliations

Better Safe than Sorry: Interlinked Feedback Loops for Robust Mitophagy

Authors

Affiliations

Abstract

Comment on

Publication types

MeSH terms

Substances

Grants and funding

LinkOut - more resources

Full Text Sources

Miscellaneous