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Case Reports
. 1989 Jan;20(1):89-91.
doi: 10.1016/0046-8177(89)90210-4.

Novel histopathologic findings in a surviving case of hemolytic uremic syndrome after bone marrow transplantation

M J Arends  1 , D J Harrison
Affiliations
Case Reports

Novel histopathologic findings in a surviving case of hemolytic uremic syndrome after bone marrow transplantation

M J Arends et al. Hum Pathol. 1989 Jan.

Abstract

We report novel renal histopathologic features in a patient with hemolytic uremic syndrome after allogeneic bone marrow transplantation who survived with plasma exchange therapy. This distribution of vascular lesions within the kidney differed from previously described cases, which were uniformly fatal, in that there were marked arterial changes in addition to arteriolar and glomerular microangiopathy. A high rate of frequency of apoptotic cells within glomeruli was found. These findings are discussed in terms of their pathogenetic and prognostic relevance.

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