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Comment
. 2015 Oct 5;13(10):e1002268.
doi: 10.1371/journal.pbio.1002268. eCollection 2015 Oct.

Dual-Function Exocytosis Regulator Has Yet Another Job

Richard Robinson  1
Affiliations
Comment

Dual-Function Exocytosis Regulator Has Yet Another Job

Richard Robinson. PLoS Biol. .

Abstract

A new study shows that synaptotagmins, known to regulate the fusion of neurotransmitter vesicles with synaptic membranes, are also needed for the prior tethering and priming of vesicles. Read the Research Article.

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Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Fig 1
Fig 1. Simultaneous ablation of Syt1 and Syt7 reduces the size of the RRP of synaptic vesicles.
Image credit: Dick Wu, Xinran Liu, and Thomas Südhof.
See this image and copyright information in PMC

Comment on

References

    1. Bacaj T, Wu D, Burré J, Malenka RC, Liu X. Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles. PLoS Biol. 2015;13(10): e1002267. - PMC - PubMed

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