Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jan;144(Pt B):287-293.
doi: 10.1016/j.neuroimage.2015.09.060. Epub 2015 Oct 9.

The Washington University Central Neuroimaging Data Archive

Affiliations

The Washington University Central Neuroimaging Data Archive

Jenny Gurney et al. Neuroimage. 2017 Jan.

Abstract

Since the early 2000's, much of the neuroimaging work at Washington University (WU) has been facilitated by the Central Neuroimaging Data Archive (CNDA), an XNAT-based imaging informatics system. The CNDA is uniquely related to XNAT, as it served as the original codebase for the XNAT open source platform. The CNDA hosts data acquired in over 1000 research studies, encompassing 36,000 subjects and more than 60,000 imaging sessions. Most imaging modalities used in modern human research are represented in the CNDA, including magnetic resonance (MR), positron emission tomography (PET), computed tomography (CT), nuclear medicine (NM), computed radiography (CR), digital radiography (DX), and ultrasound (US). However, the majority of the imaging data in the CNDA are MR and PET of the human brain. Currently, about 20% of the total imaging data in the CNDA is available by request to external researchers. CNDA's available data includes large sets of imaging sessions and in some cases clinical, psychometric, tissue, or genetic data acquired in the study of Alzheimer's disease, brain metabolism, cancer, HIV, sickle cell anemia, and Tourette syndrome.

Keywords: Alzheimer's disease; Anonymization; Archive; Brain metabolism; CNDA; Cancer; Central Neuroimaging Data Archive; Controls; Data; Database; De-identify; HIV; Imaging; Informatics; JAAT; Multi-center; Multi-site; Neuroinformatics; Pipeline; Sharing; Sickle-cell anemia; Tourette syndrome; Washington University; XNAT.

PubMed Disclaimer

Figures

Figure 1
Figure 1
JAAT Clinical Pull Template
Figure 2
Figure 2
a CNDA Projects by Year b CNDA Subjects by Year c CNDA Image Sessions by Year
Figure 2
Figure 2
a CNDA Projects by Year b CNDA Subjects by Year c CNDA Image Sessions by Year
Figure 2
Figure 2
a CNDA Projects by Year b CNDA Subjects by Year c CNDA Image Sessions by Year
Figure 3
Figure 3
a CNDA Image Sessions by Modality b CNDA Non-Imaging Data Types
Figure 3
Figure 3
a CNDA Image Sessions by Modality b CNDA Non-Imaging Data Types
Figure 4
Figure 4
CNDA Image Sessions by Scanner Manufacturer
Figure 5
Figure 5
CNDA Image Sessions by Topic of Study

References

    1. Ances BM, Ortega M, Vaida F, Heaps J, Paul R. Independent Effects of HIV, Aging, and HAART on Brain Volumetric Measures. J Acquir Immune Defic Syndr. 2012;59:469–477. - PMC - PubMed
    1. Baker LM, Paul RH, Heaps JM, Westerhaus E, Chang JY, Williams S, Brier MR, Plax K, Ances BM. Impact of human immunodeficiency virus on neurocognition and risky behaviors in young adults. J Neurovirol. 2014;20:466–473. - PMC - PubMed
    1. Coats M, Morris JC. Antecedent Biomarkers of Alzheimer’s Disease: The Adult Children Study. J Geriatr Psychiatry Neurol. 2005;18:242–244. - PubMed
    1. Doran SJ, d’ Arcy J, Collins DJ, Andriantsimiavona R, Orton M, Koh D-M, Leach MO. Informatics in radiology: development of a research PACS for analysis of functional imaging data in clinical research and clinical trials. Radiographics. 2012;32:2135–2150. - PubMed
    1. Fischl B. FreeSurfer. Neuroimage. 2012;62:774–781. - PMC - PubMed

Publication types