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. 2015 Oct 6;22(4):543-5.
doi: 10.1016/j.cmet.2015.09.020.

Sugar? No Thank You, Just a Deep Breath of Oxygen for Cancer Stem Cells

Andrea Viale  1 , Giulio F Draetta  2
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Sugar? No Thank You, Just a Deep Breath of Oxygen for Cancer Stem Cells

Andrea Viale et al. Cell Metab. .
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Abstract

Tumors are metabolically heterogeneous, and subpopulations of tumorigenic cells have been recently described to rely more on mitochondrial respiration than glycolysis for energy production. In this issue, Sancho et al. (2015) demonstrate that MYC is a master switch regulating metabolic programs in different subpopulations of pancreatic tumor cells.

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