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Case Reports
. 2015 Dec;193(6):1051-4.
doi: 10.1007/s00408-015-9817-4. Epub 2015 Oct 7.

Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual "Headcheese Pattern" with Nodules

V Pietrangeli  1   2 , S Piciucchi  3 , S Tomassetti  1 , C Ravaglia  1 , C Gurioli  1 , Ch Gurioli  1 , A Cavazza  4 , A Dubini  5 , V Poletti  1   6
Affiliations
Case Reports

Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual "Headcheese Pattern" with Nodules

V Pietrangeli et al. Lung. 2015 Dec.

Abstract

A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered.

Keywords: Chromogranin; DIPNECH; Headcheese pattern; UIP pattern.

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References

    1. N Engl J Med. 1992 Oct 29;327(18):1285-8 - PubMed
    1. J Thorac Imaging. 2014 Jan;29(1):W13 - PubMed

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